What is Filaggrin?

What is Filaggrin?

Filaggrin is a protein that is essential for skin hydration and integrity of the skin barrier. It is largely responsible for how well your skin retains moisture, and determines how hydrated and healthy your skin is. Filaggrin is essential for the production of Natural Moisturising Factor (NMF) – substances that maintain skin hydration and skin barrier function.


People with eczema-prone skin may be deficient in the gene for making Filaggrin which may result in a shortage of this protein. A lack of Filaggrin makes it easier for moisture to escape as your skin barrier is compromised, making your skin vulnerable and prone to dehydration.




Cetaphil PRO AD Derma is the first skincare range* with Filaggrin technology™ to help restore your skin’s Natural Moisturising Factor and help rebuild a healthy skin barrier. This in turn helps soothe your skin and reduces itchiness, which aids in stopping the itch-scratch cycle for people with eczema-prone skin. By hydrating and strengthening the skin’s barrier function, Cetaphil PRO AD Derma provides relief from itch and redness for eczema-prone skin.


*Within Cetaphil’s range of skincare products